RRAM

Risk modelling for quality improvement in the critically ill: making best use of available data – RRAM study

Description

To establish the clinical and health economic effects of moving from systemic heparin anticoagulation to regional citrate anticoagulation for continuous renal replacement therapy for patients treated for acute kidney injury on non-specialist ICUs in England and Wales by linking routinely collected data sources.

Objectives:
1. Investigate the short-term benefits, risks, and costs of citrate anticoagulation.
2. Provide information on the subsequent development of end-stage renal disease (ESRD).
3. Trial the efficient research techniques, that if successful could be used to track the effects of any change in critical care practice occurring in ICUs in England and Wales over a reasonably short time scale.

UKRR data are to be used for objective 2.

Data supplied from UKRR

To be shared with NHS Digital for third party data linkage (for all patients with ERF diagnosed at any time up to 31 March 2017 and alive at 1 April 2009):

  • Local identifier (for linkage back to UKRR clinical data)
  • IDN01 (Patient Surname)
  • IDN02 (Patient Forename)
  • IDN03 (Date of birth)
  • PAT00 (Sex)
  • PAT13 (NHS Number)
  • PAT23 (Postcode)

 

To be shared with ICNARC (for linked patients only):

  • Common identifier (supplied by NHS Digital)
  • PAT33 (Date first seen by Renal Physician)
  • Date of FIRST EVER renal replacement therapy
  • FIRST EVER renal replacement modality
  • TXT00 – Date of start of treatment
  • TXT01 – Date of end of treatment
  • TXT02 – Treatment modality code
  • Transplant date
  • Transplant number
  • Graft type
  • PAT40 – Date of death – set to 15th of the month
  • PAT42 – Main cause of death 1
  • PAT43 – Cause of death 2
  • PAT44 – Cause of death free text
  • QHD00 – Date of HD/PEX session
  • QHD41 – Haemodialysis/ Plasma exchange
  • ERFAJ – New ERA-EDTA primary renal diagnosis
  • ERF04 – EDTA primary renal diagnosis
  • ERF07 – Secondary renal disease code
  • ERF09 – Primary renal disease free text if no code is available

Who

Doug Gould <Doug.Gould@icnarc.org> - Senior Researcher


Files

Data Sharing Agreement for UKRR DSA62 R:\0 Information Governance\Data sharing agreements (DSAs)\DSAs\Current DSAs\DSA62 Harrison_ICNARC_RRAM

Documents from IGNARC in R:\0 Systems\Projects\RRAM

Data Extract files and code in Q:\Data Sets\2019-01-10 DSA62